GRK2243 Symposium

Understanding Ubiquitylation:

From Molecular Mechanisms to Disease

4-6 May 2020 I Würzburg, Germany 


The Meeting

The post-translational modification of proteins with ubiquitin ("ubiquitylation") has taken center stage in eukaryotic cell biology. Ubiquitylation mediates the degradation of regulatory and damaged proteins, protein aggregates and even entire organelles. Moreover, it controls a wide variety of non-proteolytic processes, e.g. during DNA damage repair, receptor signaling and endocytosis.


Given the multi-faceted cellular functions of protein ubiquitylation, it is not surprising that abnormalities of the ubiquitin system lead to many human diseases including cancer, neurodegenerative disorders and infectious diseases. Moreover, the ubiquitin system has emerged as a promising target for therapeutic intervention, and drugs interfering with ubiquitin-mediated proteolysis are successfully used for the treatment of certain cancers. 


This Symposium aims to showcase the most recent, exciting progress towards understanding molecular mechanisms, cellular functions and pathogenic aberrations of the ubiquitin system as well as developing novel therapeutic strategies targeting it. The meeting will feature cutting-edge research presentations by international leaders in the field, additional short talks selected from submitted abstracts, and a large poster session along with poster teasers. There will be ample opportunity for scientific interactions between all participants to stimulate further progress in ubiquitin research.


The Symposium is organized by the Research Training Group GRK2243, a ubiquitin-themed graduate program, which has been funded by the German Research Foundation DFG since April 2017. The GRK2243 offers cutting-edge research projects and a structured, interdisciplinary training program for more than 30 PhD students and postdocs at the University of Würzburg.

For further information, please visit our webpage:


1 February 2020



15 March 2020

Short talks will be selected from abstracts.

  • Twitter - Weiß, Kreis,

Find us on Twitter:


Application will be open in due time.



For further information, please click on the speakers’ portraits.

David Barford
Anne Bertolotti
Bruce Clurman
University of Washington, USA
Craig Crews
Yale University, USA
Ivan Dikic
Goethe University Frankfurt, DE
Wade Harper
Harvard University, USA
Thorsten Hoppe
University of Cologne, DE
Rachel Klevit
University of Washington, USA
Elke Krüger
University Medicine Greifswald, DE
Yogesh Kulathu
University of Dundee, UK
Andreas Martin
UC Berkeley, USA
Frauke Melchior
Heidelberg University, DE
Hemmo Meyer
University of Duisburg-Essen, DE
Anna Sablina
VIB-KU Leuven, B
Titia Sixma
Netherlands Cancer Institute, NL
Jesper Svejstrup
The Francis Crick Institute, UK
Nicolas Thomä
Friedrich Miescher Institute, CH
Helle Ulrich
IMB Mainz, DE
Sylvie Urbé
University of Liverpool, UK
Cynthia Wolberger
John Hopkins University, USA
Show More


Day 1 - 4 May 2020
Day 2 - 5 May 2020
Day 3 - 6 May 2020

Registration & Fees


1 February 2020


15 March 2020

Registration fees

PhD student, Postdoc                      100 €

Academic                                          150 €

Industry                                             250 €

Application will be open in due time.

Registration includes:

  • Conference materials

  • Access to all sessions

  • Conference dinner at Bürgerspital

  • Food and drinks during coffee breaks, lunches and finger food during poster session


Accommodation is not included. Please see hotel registration information under LOCATION below.


Please note that payment must be submitted only after receipt of confirmation that your registration has been accepted. At that point, you will receive an email from the organizers with detailed payment instructions. Payment ought to be made via national and international bank transfer exclusively. Credit card payment is not possible.


Cancellation and registration fee refund policy:

  1. Notification of cancellation should be made in writing and sent to the conference organizers:

  2. 100% refund (less 25 € handling fee) if a notification e-mail reaches the organizers on or before
    15 March 2020.

  3. No refund on cancellations after 15 March 2020.

Selection criteria

The admission of participants (in case of overbooking) will be guided by the submitted abstracts, according to the expected scientific impact of the work on the conference and the field. It is thus recommended that all participants submit an abstract at the time of registration and specify whether they wish to present a poster or short talk.


For participants who do not plan to present their work, a CV (for principal investigators) or motivation letter (for students/post-docs) is requested.

Abstract guidelines


Please download the abstract template and follow the instructions therein. 

Poster specifications


Please bring one printed copy of your poster in portrait orientation (not landscape). 


Short talks


A number of short talks (10 min talk followed by 5 min discussion) – preferentially by early-career scientists – will be selected from the submitted abstracts ahead of the meeting.

Please indicate whether you would like to be considered for a short talk at the time of registration. Applicants will be notified at least three weeks before the meeting.


Coordinator GRK2243: Julia Seubert 



Organizing committee

Alexander Buchberger

Biocenter, University of Würzburg

Sonja Lorenz

Rudolf Virchow Center, University of Würzburg

Thomas Rudel

Biocenter, University of Würzburg

Hermann Schindelin

Rudolf Virchow Center, University of Würzburg

Oliver Hartmann

Biocenter, University of Würzburg

Sophie Hügelschäffer

Biocenter, University of Würzburg

Carina Maier

Biocenter, University of Würzburg

Radhika Karal Nair

Rudolf Virchow Center, University of Würzburg

Michaela Reißland

Biocenter, University of Würzburg


Meeting Venue

Tagungszentrum Festung Marienberg

Oberer Burgweg 40

97082 Würzburg


For further information, please check:

(German website only)

Tim Köhler

Arrival and parking at the Marienberg Fortress

By car: Please enter the destination "Oberer Burgweg" in the navigation system. At the entry to the Marienberg Fortress (about 5 min walking distance to the conference center), there is a chargeable car park with 150 slots.


By public transport: Take bus number 9 from "Residenz" via "Juliuspromenade" (operates between 9:30 am and 6:30 pm). Alternatively, and for longer operating hours, take bus number 18 from the central bus station (next to main train station) to "Oberer Burgweg" and walk ca. 500m to the Marienberg Fortress.


By foot: From the city center, walk to the "Alte Mainbrücke" and follow the sign-posted walkway (15-20 min walk, quite steep in part).


Please note that accommodation is not included in the registration fee and has to be organized by the participants on their own.

For the three nights, May 3-6, 2020, participants are offered special conditions at the Ghotel (incl. breakfast): single room for 85 €/per night and double room for 105 €/per night. Please make your reservation directly with the hotel, using code GRK2243. A limited number of rooms have been reserved for the conference and will be available on a first-come-first-serve basis until March 9, 2020.


For further accommodation opportunities, please check here:

About Würzburg

For further information, please check the official tourist information website of Würzburg:

Copyright: Peter Schumann (cover image,, Congress-Tourismus-Würzburg & Katrin Heyer



Industrial Sponsors

© 2019 by the GRK2243. Proudly created with help of SCIGRAPHIX.